Total cholesterol, LDL-cholesterol, apolipoprotein-B, apolopoprotein-A1, For years, the concentration of low-density lipoprotein (LDL-cholesterol) in blood serum has served as the go-to measure of cardiovascular disease risk. However, researchers have noted that LDL-cholesterol contains several constituents (small, dense vs. large, buoyant particles), which predict higher and lower risks for cardiovascular disease, respectively. More recently, researchers have…
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Saturated Fats and Dietary Guidelines for Americans
The diet-heart hypothesis Starting in the late 1950s, University of Minnesota physiologist Ancel Keys developed the idea that fats and, subsequently, saturated fats increased blood serum levels of cholesterol and LDL-cholesterol. Many studies show significant associations between elevated blood serum LDL-cholesterol levels and increased risk of cardiovascular disease. Thus, reducing dietary intake of saturated fats…
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